Reversibility of Cisplatin-induced Hearing Loss
نویسندگان
چکیده
منابع مشابه
Magnetic Nanoparticle Mediated Steroid Delivery Mitigates Cisplatin Induced Hearing Loss
Cisplatin (cis-diamminedichloroplatinum) is widely used as a chemotherapeutic drug for genitourinary, breast, lung and head and neck cancers. Though effective in inducing apoptosis in cancer cells, cisplatin treatment causes severe hearing loss among patients. Steroids have been shown to mitigate cisplatin-induced hearing loss. However, steroids may interfere with the anti-cancer properties of ...
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Although there are many factors that contribute to a patient’s response to therapy, genetic factors account for a significant proportion of variability in drug response and are estimated to play a role in at least half of all adverse drug reactions (ADRs) (1). Genetic variability in drug metabolizing enzymes and transport systems involved in absorption, distribution, excretion and metabolism ma...
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This paper presents noise problems associated with the use of air-turbine drills in dental practice. Two hundred and fifty dentists (male and female) were randomly selected from the faculty of dentistry as well as the dentists who worked private in Tehran. The results indicated that the mean value of sound pressure level produced by the high-speed drills was 69.1 db. Most of the energy from...
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Osteoporosis is not usually considered to be reversible, as it is a consequence of the ageing process. However, an improvement of bone mineral density after successful surgery in Cushing's syndrome has been shown in several reports. The question of reversibility of exogenous corticosteroid-induced osteoporosis is, as yet, unanswered, possibly because of the difficulty in discontinuing steroids ...
متن کاملPrediction of Hearing Loss Due to Cisplatin Chemoradiotherapy.
IMPORTANCE Patients with head and neck cancer may experience chemoradiotherapy-induced hearing loss, but the weighing of involved variables has been subjective. Identification of patient and treatment characteristics to predict the absolute posttreatment hearing level is important for effective counseling of patients undergoing chemoradiotherapy. OBJECTIVE To predict treatment-induced hearing...
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ژورنال
عنوان ژورنال: AUDIOLOGY JAPAN
سال: 2003
ISSN: 1883-7301,0303-8106
DOI: 10.4295/audiology.46.157